|
|
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> eicosapentaenoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
MK
|
|
BRENDA:
BR51509
KEGG:
R11060
MetaCyc:
RXN-13429
|
|
|
|
eicosapentaenoic_acid + ATP + CoA <=> eicosapentaenoyl-CoA + diphosphate + AMP
|
6.2.1.3
long-chain-fatty-acid---CoA ligase
|
–
|
|
|
BRENDA:
BS283
MetaCyc:
RXN-12978
|
|
|
|
eicosapentaenoyl-CoA + H2O <=> eicosapentaenoic_acid + CoA + H+
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
|
–
–
|
K
|
|
BRENDA:
BS360759
KEGG:
R08179
MetaCyc:
RXN-13430
|
|
|
|
malonyl-CoA + eicosapentaenoyl-CoA + H+ <=> (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + CoA + CO2
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-13442
|
|
|
|
[glycerolipid]-(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate + CoA <=> eicosapentaenoyl-CoA + glycerolipid
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-17688
|
|
|
|
eicosapentaenoyl-CoA + hexadecanol <=> CoA + eicosapentaoenoyl_hexadecanate
|
2.3.1.75
long-chain-alcohol O-fatty-acyltransferase
|
–
|
|
|
BRENDA:
BS455612
|
|
|
|
eicosapentaenoyl-CoA + 1-acyl-lysophosphatidic_acid <=> CoA + 1-acyl-2-eicosapentaenoyl-lysophosphatidic_acid
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS454392
|
|
|
|
eicosapentaenoyl-CoA + 1-oleoyl-sn-glycerol_3-phosphate <=> CoA + 2-eicosapentaenoyl-1-oleoyl-sn-glycerol_3-phosphate
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS445468
|
|
|
|
eicosapentaenoyl-CoA + sn-glycerol_3-phosphate <=> CoA + 1-eicosapentaenoyl-sn-glycerol_3-phosphate
|
2.3.1.15
glycerol-3-phosphate 1-O-acyltransferase
|
–
|
|
|
BRENDA:
BS420652
|
|
|
|
eicosapentaenoyl-CoA + diacylglycerol <=> CoA + 1,2-diacyl-3-eicosapentaenoylglycerol
|
2.3.1.20
diacylglycerol O-acyltransferase
|
–
|
|
|
BRENDA:
BS455610
|
|
|
|
ATP + eicosapentaenoic_acid + CoA <=> ATP + diphosphate + eicosapentaenoyl-CoA
|
6.2.1.15
arachidonate---CoA ligase
|
–
|
|
|
BRENDA:
BS179
|
|
|
|
linolenoyl-CoA + ferricytochrome_b5 + O2 + H+ <=> eicosapentaenoyl-CoA + ferricytochrome_b5 + H2O
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
|
|
BRENDA:
BS433406
|
|
|
|
eicosatetraenoyl-CoA + ferricytochrome_b5 + O2 + H+ <=> eicosapentaenoyl-CoA + ferricytochrome_b5 + H2O
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
|
|
BRENDA:
BS433701
|
|